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berberine) often exert anti-inflammatory effects by inhibiting pro-inflammatory signaling pathways like NF-B, MAPK, and PI3K/Akt (Shen S

These concerns have sparked international debate about the adequacy of current standard preoperative fasting guidelines in the context of the gastrointestinal motordepressant effects of GLP-1 RAs, leading to the issuance of updated clinical recommendations [48]

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The substantial majority of human research has been conducted in Russia and Eastern Europe and consists predominantly of observational rather than randomized controlled studies